The Biomedical Research Centre

Journal Articles

Clark, B.J., Cote, H.C.F., Cool, D.E., Clark-Lewis, I., Pixley, R.A., Colman, R.W., Saito, H., and MacGillivray, R.T.A. Mapping of a putative surface binding site of human coagulation factor XII, J. Biol. Chem. 264: 11497-11502, 1989.

Duronio, V., and Pelech, S.L. Interleukin 3 stimulates the turnover of phosphatidylcholine in the mast cell/megakaryocyte line R6-XE.4. Biochem. Biophys. Res. Commun. 164: 804-808, 1989.

Dycaico, J.M., Grant, S., Felts, K., Nichols, W.S., Geller, S.A. Pollard, A.J., Kohler, S.W., Short, H.P., Jirik, F.R., Hanahan, D., and Sorge J.A. Neonatal hepatitis induced by alpha1-antitypsin: A transgenic mouse model. Science 242: 1409-1412, 1989.

Gautam, N., Baetsher, M., Aebersold, R. and Simon, M.C. A G-protein gamma subunit shares homology with ras proteins. Science 244: 971-974, 1989.

Jirik, F.R., Podor, T.J., Hirano, T., Kishimoto, T., Luskutoff, D.J., Carson, D.A. and Lotz, M. Bacterial lipopolysaccharide and inflammatory mediators augment interleukin-6 secretion by human endothelial cells. J. Immunol. 242: 144-147, 1989.

Leslie, K.B. and Schrader, J.W. Growth Factor Gene Activation and Clonal Heterogeniety in an autostimulatory myeloid leukemia. Mol. Cell. Biol. 6: 2414-2423, 1989.

Liew, F.Y., Milot, S., Li, Y., Lelchuk, R., Chan, W.L. and Ziltener, H.J. Macrophage activation by IFN-g from host-protective T cells is inhibited by IL-3 and IL-4 produced by disease-promoting T cells in leishmaniasis. Eur. J. Immunol. 19: 1227-1232, 1989.

Lotz,M., Zuraw, B.L., Carson, D.A., Jirik, F.R. Hepatocytes produce interleukin-6. Ann. NY Acad. Sci. 557: 509-511, 1989.

Pelech, S.L. Cellular security: How anti-cancer genes turn off tumors. The Sciences (N.Y. Academy of Sciences) 29: 38-44, 1989.

Pelech, S.L. and Vance, D.E. Signal transduction via phosphatidylcholine cycles. Trends Biochem. Sci. 14: 28-30, 1989.

Pelech, S.L., Paddon, H.B., Kwong, L.C. and Weeks, G. Characterization of developmentally regulated cAMP/Ca2+- independent protein kinases from Dictyostellium discoideum. Dev. Growth Differ. 31: 351-361, 1989.

Podor, T.J., Jirik, F.R., Loskutoff, D.J., Carson, D.A. and Lotz, M. Human endothelial cells produce IL-6: Lack of responses to exogenous IL-6. Ann. NY Acad. Sci. 557: 374-387, 1989.

Vadas, M.A., Lopez, A.F., Shannon, M.F. and Clark-Lewis, I. Regulation of eosinophilopoiesis in man. In: Eosinophils and Asthma, pp. 1-17, 1989.

Walker, C., Nettesheim, P., Barrett, J., Jirik, F.R., Sorge, J., Joyce, M. and Gilmer, T. Mouse sequences acquired by cell lines after passaging through nude mice detected by hybridization of the fms probe pSM-3. Cancer Research, 49: 625-628, 1989.

Woo, D.D.L., Clark-Lewis, I., Chait, B.F. and Kent, S.B.H. Chemical synthesis in protein engineering: Total synthesis purification and covalent structural characterization of a mitogenic protein, human transforming growth factor-alpha. Protein Engineering, 3: 29-37, 1989.

Yamamori, T., Fukada, K., Aebersold, R., Korsching, S., Fann, M.-J. and Patterson, P. The cholinergic neuronal differentiation factor is identical to the Leukemia inhibitory factor. Science 246: 1412-1416, 1989.

Ziltener, H.J., Clark-Lewis, I. and McDonald, S.L. Sandwich enzyme immunoassay for murine IL-3. Cytokine 1: 56-61, 1989.

Books and Book Chapters

Aebersold, R. Internal amino acid sequence analysis of proteins after "In situ" protease digestion on nitrocellulose. In: A Practical Guide to Peptide and Protein Purification for Microsequencing, ed. P. Matsudaira, Academic Press, pp73-85, 1989.

Aebersold, R. Sequence analysis of proteins separated by Polyacrylamide Gel Electrophoresis. In: Electrophoresis Forum. '89, ed. BJ Radola, Technical University, Munich Press, pp60-71, 1989.

Schrader, J.W. Introduction In: Peptide Regulatory Factors, ed. Evans, I., The Lancet, 1989.

Schrader, J.W., Clark-Lewis, I., Fazekas, B., Hood, L.E., Kent, S.B.H., Leslie, K.B., Schrader, S. and Ziltener, H.J. Structure and function of the pan-specific hemopoientin Interleukin-3. In: Integration and Control of Metabolic Process: Pure and Applied Aspects. ed. Kon, O.L., Cambridge University Press, Cambridge, England, pp. 211-219, 1989.

Schrader, J.W., Leslie, K.B., Orban, P.C. and Ziltener, H.J. Growth Factors in leukemogenesis. In: NATO Advanced Study Institute series on Cell Biology, Viruses as tools for the study of normal and abnormal growth and differentiation. (ed. H. Lother) Springer-Verlag Heidelberg, pp 221-227, 1989.