The Biomedical Research Centre

Journal Articles

Aebersold, R. Solid-phase protein sequence analysis. Nature 343: 291-292, 1990.

Aebersold, R. and Leavitt, J. Sequence analysis of proteins separated by polyacrylamide gel electrophoresis: Towards an integrated protein database. Elecrophoresis 11: 517-527, 1990.

Aebersold, R. and Morrison, M.D. Separation of dilute peptide samples by capillary zone electrophoresis. J. Chromatogr. 516, 79-88, 1990.

Aebersold, R., Pipes, G., Wettenhall, R.E.H., Nika, H. and Hood, L.E. Covalent attachment of peptides for high sensitivity solid-phase sequence analysis. Anal. Biochem. 187: 56-65, 1990.

Carroll, M.P., Clark-Lewis, I., Rapp, U.R. and May, S.W. Interleukin-3 and granulocyte macrophage colony stimulating factor mediate rapid phosphorylation and activation of cytosolic c-raf. J. Biol. Chem. 265: 19812-19817, 1990.

Chaikin, E., Ziltener, H.J., Razin, E. Protein kinase C plays an inhibitory role in IL-3- and IL-4-mediated mast cells proliferation. J. Biol. Chem. 268: 22109-22116, 1990.

Clark-Lewis, I. Structure function studies of interleukin-3, In: Peptides: Structure and Biology Proceedings of the 11th North American Peptide Symposium, eds. Rivier, J.E. and Marshall, G.R., Escom, Leiden, The Netherlands, pp. 749-750, 1990.

Gamble, J.R., Rand, T., Lopez, A.F., Clark-Lewis, I. and Vadas, M.A. Heterogeneity of recombinant granulocyte macrophage colony stimulating factor mediated enhancement of neutrophil adherence to endothelium. Exp. Hematol. 8: 897-962, 1990.

Jirik, F.R., Janzen, N.M., Melhado, I.G., Harder, K.W. Cloning and chromosomal assignment of a widely expressed human receptor-like protein-tyrosine phosphatase. FEBS Lett., 273: 239-242, 1990.

Kalmar, G.B., Kay, R.J., Lachance, A., Aebersold, R. and Cornell, R.P. Cloning and expression of rat liver cytidylyl transferasse: An amphipathic protein that controls phospholidyl choline synthesis. Proc. Natl. Acad. Sci. 871: 6029-6033, 1990.

LeGros, G., Ben-Sasson, S.Z., Conrad, D.H., Clark-Lewis, I., Finkelman, F.D., Plaut, M. and Paul, W.E. IL-3 promotes production of IL-4 by splenic Non-B, Non-T cells in response to Fc receptor cross-linkage. J. Immunol. 145: 2500-2506, 1990.

Ling, Z-D, Ziltener, H.J., Webb, B.T. and Matheson, D.S. Aggregated immunoglobulin and Fc fragment of IGG induce IL-6 release from human monocytes. Cell. Immunol. 129: 95-103, 1990.

Moser, B., Clark-Lewis, I., Zwahlen, R. and Baggiolini, M. Neutrophil activating properties of the melanoma growth stimulating activity (MGSA). J. Exp. Med. 171: 1797-1802, 1990.

Pelech, S.L. When cells divide. Biologists identify the universal pacemaker
of mitosis. The Sciences (N.Y. Academy of Sciences) 30: 22-28, 1990.

Pelech, S.L., Sanghera, J.S. and Daya, M. Protein kinase cascades in meiotic and mitotic cell cycle control. Biochem. Cell Biol. 68: 1297-1330, 1990.

Pelech, S.L., Paddon, H.B., Charest, D.L. and Federsppiel, B.S. Interleukin 3 induced activation of protein kinases in the mast cell/megakaryocyte R6-XE4 line. J. Immunol. 144: 1759-1766, 1990.

Salari, H., Duronio, V., Howard, S., Demos, M. and Pelech, S.L. Translocation-independent activation of protein kinase C by platelet activating factor, thrombin and prostacyclin. Biochem. J. 267: 689-696, 1990.

Salari, H., Duronio, V., Howard, S., Demos, M., Jones, K., Reany, A., Hudson, A.T. and Pelech, S.L. Erbstatin blocks platelet activating factor-induced protein-tyrosine phosphorylation, polyphosphoinositide hydrolysis, protein kinase C activation, serotonin secretion and aggregation of rabbit platelets. FEBS Lett. 263: 104-108, 1990.

Sanghera, J.S., Aebersold, R., Morrison, H.D., Bures, E.J. and Pelech, S.L. Identification of the sites in myelin basic protein that are phosphorylated by maturation -activated p44mpk by solid phase-sequence analysis. FEBS Lett. 273: 223-226, 1990.

Sanghera, J.S., Paddon, H.B., Bader, S.A. and Pelech, S.L. Purification and characterization of a maturation-activated myelin basic protein kinase from sea star ocytes. J. Biol. Chem. 265: 52-57, 1990.

Withers, S.G., Warren, A.J., Street, I.P., Rupitz, K., Kempton, J.B., and Aebersold, R. Unequivocal demonstration of the involvement of a glutamate residue as a nucleophile in the mechanism of a glyosidase. J. Americ. Chem. Soc., 122, 5887-5889, 1990.

Ziltener, H.J., Babcook, J., Well, R. Development of a particle concentration fluorescence immunoassay for Interleukin-6. Proceedings Pandex User Meeting (Baxter/Pandex Division) pp 73-83, 1990.

Books and Book Chapters

Aebersold, R. Sequence analysis of proteins separated by polyacrylamide gel electrophoresis. Advances in Electrophoresis, eds M.J. Dunn, B.J. Radola. VCH, Verlag, vol. 4, pp 1-89, 1990.

Schrader, J.W., Leslie, K.B., Orban, P.C. and Ziltener, H.J. Tumor treatment and cytokines In: Effects of therapy on biology and kinetics of the residual tumor, Part B: Clinical Aspects, eds. Ragaz, J., Simpson-Herren, L., Lippman, M.E. and Fisher, B., Wiley-Liss, Inc., New York, N.Y. pp19-27, 1990.