The Biomedical Research Centre

Journal Articles

Abraham, K.M, Levin, S.D., Marth, J.D., Forbush, K.A. and Perlmutter, R.M. Thymic tumorigenesis induced by overexpression of p56lck. Proc. Natl. Acad. Sci. USA 88: 3977-3981, 1991.

Abraham, K.M., Levin, S.D., Marth, J.D., Forbush, K.A. and Perlmutter, R.M. Delayed thymocyte development induced by augmented expression of p56lck. J. Exp. Med. 173: 1421-1432, 1991.

Aebersold, R., Watts, J., Morrison, H.D., and Bures, J.E. Determination of the site of tyrosine phosphorylation at the low picomole level by solid-phase sequence analysis. Anal. Biochem. 1999: 51-60, 1991.

Babcook, J., Watts, J., Aebersold, R., and Ziltener, H.J. Automated, non-isotopic assay for protein tyrosine kinases and protein tyrosine phosphatases. Anal. Biochem. 196: 245-251, 1991.

Barber, D.L., Sanders, E.J., Aebersold, R., and Schneider, W.J. The receptor for yolk lipoprotein recognition in the chicken oocyte. J. Biol. Chem. 266: 18761-18770, 1991.

Chung, J., Pelech, S.L. and Blenis, J. Mitogen-activated Swiss mouse 3T3 rsk kinases I and II are related to pp44mpk from sea star oocytes and participate in the regulation of p90rskactivity. Proc. Natl. Acad. Sci. USA 88: 4981-4985, 1991.

Clark-Lewis, I., Moser, B., Walz, A., Baggiolini, M., Scott, G.J. and Aebersold, R. Chemical synthesis, purification and characterization of two inflammatory proteins, neutrophil activating peptide-1 (Interleukin 8) and neutrophil activating peptide-2. Biochemistry 30: 3128-3135, 1991.

Clark-Lewis, I., Sanghera, J.S. and Pelech, S.L. Definition of a consensus sequence for peptide substrate recognition by p44mpk the meiosis- activated myelin basic protein kinase. J. Biol. Chem., 266: 15180-15184, 1991.

Clark-Lewis, I., Schumacher, C., Baggiolini, M. and Moser, B. Structure activity relationships of interleukin-8 determined using chemical synthesized analogs: Critical role of N-terminal residues and evidence for uncoupling of neutrophil chemotaxis, exocytosis and receptor binding. J. Biol. Chem. 262: 23128-23134, 1991.

Coull, J.M., Pappin, D.J.C., Mark, J., Aebersold, R., and Koester, M. Use of functionalized membrane supports for covalent microsequence analysis. Anal. Biochem. 194: 110-120, 1991.

Daya-Makin, M., Pelech, S.L., Levitzki, A., and Hudson, A.T. Erbstatin and tyrophostins block protein-serine kinase activation and meiotic maturation of sea star oocytes. Biochim. Biophys. Acta 1093: 87-94, 1991.

Detmers, P.A., Powell, D.E., Walz, A., Clark-Lewis, I., Baggiolini, M. and Cohn, Z.A. Differential effects of neutrophil activating peptide 1/Interleukin-8 and its homologues on neutrophil adhesion and phagocytes. J. Immunol. 147: 4211-4217, 1991.

Duronio, V., Granleese, S.R., Clark-Lewis, I., Schrader, J.W. and Ziltener, H. Antibodies to IL-3 as probes for the IL-3 receptor and for mapping of IL-3 interaction with receptor. Cytokine 3: 414-420, 1991.

Gilkes, N.R., Claeyssens, M., Aebersold, R., Henrissat, B., Meinke, A., Horinouchi, S., Morrison, H.D., Kilburn, D.G., Warren, A.J. and Miller, R.C. Structural and functional comparisons of b1,4 glycanases from families B and F, including assignment of disulfide bonds in CenA and Cex from Cellulomonas Fimi. European J. of Biochem. 202: 367-377, 1991.

Hockertz, M.K., Clark-Lewis, I. and Candido, E.P.M. Studies of the small heat shock proteins of caenorhabditis elegansusing antipeptide antibodies. FEBS Letters 280:375-378, 1991.

Keller, S.E., Kitagawa, K., Aebersold, R., Lienhard, G.E. and Garner, C.E. Purification and properties of the 160,000 Da Phosphotyrosyl protein, a putative participant in insulin signaling. J. Biol. Chem. 266: 12817-12820, 1991.

Leslie, K.B. and Schrader, J.W. IAP-Mediated activations of cytokine genes in a murine myelomonocytic leukemia: Novel generation of functional cytokine mRNAs by retroviral splicing events. Mol. Cell. Biol.
11: 5562-5570, 1991.

Leslie, K.B., Ziltener, H.J. and Schrader, J.W. The role of IL-1 and GM-CSF in the paracrine stimulation of an in vivo-derived murine myeloid leukemia. Blood 78: 1301-1310, 1991.

Madden, K.B., Urban, J.F. Jr., Ziltener, H.J., Schrader, J.W., Findelman, F.D. and Katona, I.M. Antibodies to IL-3 and IL-4 suppress helminth-induced intestinal mastocytosis. J. Immunol. 147: 1387-1391, 1991.

Moser, B., Shumacher, C., von Tscharner, V., Clark-Lewis, I. and Baggiolini, M. Neutrophil-activating peptide 2 and gro/melanoma growth-stimulating activity interact with neutrophil-activating peptide 1/interleukin-8 receptors on human neutrophils. J. Biol. Chem. 266: 10666-10671, 1991.

Patel, S.D., Aebersold, R. and Attardi, G. CDNA-derived amino acid sequence of the NADH-binding 51 kDa subunit of the bovine respiratory NADH dehydrogenase reveals striking similarities to a bacterial NAD+ reducing hydrogenase. Proc. Natl. Sci. USA 88: 4225-4229, 1991.

Patterson, S.D. and Aebersold, R. Efficient recovery of gel electrophoresis separated proteins after electroblotting onto a cationic membrane. Proceedings of the International Meeting on Transdimersional Electrophoresis, ed. MJ Dunn, pp 105-110, 1991.

Pelech, S.L., Samiei, M., Charest, D.L., Howard, S.L. and Salari, H. Production of calcium-independent forms of protein kinase C-b in phorbol ester-treated rabbit platelets. J. Biol. Chem. 266: 8696-8705, 1991.

Pelech, S.L., Sanghera, J.D., Paddon, H.B., Quayle, K. and Brownsey, R. Identification of the major maturation-activated acetyl-CoA carboxylase kinase in sea star oocytes as p44mpk. Biochem. J. 274: 759-767, 1991.

Pickersky, E., Subramaniam, R., White, M.J., Reid, J. Aebersold, R. and Green, B.R. Sequence for the gene for one of the polypeptides of CP29, the interanl Chlorophyll a+b complex of Photosystem II. Mol. Gen. Genet. 227: 277-284, 1991.

Posada, J., Sanghera, J.S., Pelech, S.L., Aebersold, R. and Cooper, J. Tyrosine phosphorylation and activation of homologous protein kinases during oocyte maturation and mitogenic activation of fibroblasts. Mol. Cell. Biol. 11: 2517-2528, 1991.

Razin, E., Leslie, K.B. and Schrader, J.W. Connective tissue mast cells in contact with fibroblasts express IL-3 mRNA: Analysis of single cells by polymerase chain reaction. J. Immunol. 146: 981-987, 1991.

Rossomando, A.J., Sanghera, J.A., Arsden, L.A., Weber, M.J., Pelech, S.L. and Sturgill, T.W. Evidence for a family of serine/threonine protein kinases regulated by tyrosine and serine/threonine phosphorylations.
J. Biol. Chem. 266: 20270-20275, 1991.

Samiei, M., Makin-Daya, M., Clark-Lewis, I. and Pelech, S.L. Platelet activating factor- and thrombin-induced stimulation of p34cdc2/cyclin histone H1 kinase activity in platelets. J. Biol. Chem. 266: 14889-14892, 1991.

Sanghera, J.S., McNabb, C., Tonks, N. and Pelech, S.L. Tyrosyl phosphorylation and activation of the myelin basic protein kinase p44mpk during sea star oocyte maturation. Biochim. Biophys. Acta.
1095: 153-160, 1991.

Sanghera, J.S., Paddon, H.B. and Pelech, S.L. Role of protein phosphorylation in the maturation-induced activation of a myelin basic protein kinase from sea star oocytes. J. Biol. Chem. 266: 6700-6707, 1991.

Schrader, J.W., Moyer, C., Ziltener, H.J. and Reinisch, C.L. Release of the cytokines colony stimulating factor-1, granulocyte macrophage colony stimulating factor and interleukin-6 by cloned murine vascular smooth muscle cells. J. Immunol. 146: 3799-3808, 1991.

Schwartz, E., Shen, D., Aebersold, R., McGrath, J.M. et al. Nucleotide sequence and chromosomal location of Cab11 and Cab12, the genes for the fourth polypeptide of the photosystem I light-harvesting antenna (LHCI). FEBS Lett. 280: 229-234, 1991.

Schwartz, E., Stasys, R., Aebersold, R., McGrath, J.M., Green, B. and Pichensky, E. Sequence of a tomato gene encoding a third type of LHC II cholorphyll A/B - binding protein. Plant Mol. Biology 17: 923-925, 1991.

Smith, W.B., Gamble, J.G., Clark-Lewis, I. and Vadas, M.A. Interleukin-8 induces trans endothelial migration. Immunology 72: 65-72, 1991.

Stifani, S., Barber, D.L., Aebersold, R., Steyrer, E. et al. The laying hen expresses two different low density lipoprotein receptor-related proteins. J. Biol. Chem. 266: 19079-19087, 1991.

Suyama, K., Goldstein, J., Aebersold, R., Kent, S. Regarding the size of Rh proteins [letter], Blood, Jan 15; 77(2): 411, 1991.

te Heesen, S., Rauhut, R., Aebersold, R., Abelson, J., Aebi, M., and Clark, M.W. A 45kDa yeast transmembrane protein reacts with anti nuclear pore antibodies: purification of the protein, immunolocalization and cloning of the gene. Eur. J. Cell Biology 56: 8-18, 1991.

Tull, D., Withers, S.G., Warren, R.A.J. and Aebersold, R. Identification of the active site nucleophile of a cellulose; the cellulomonas fimi exoglucanase. J. Biol. Chem. 266: 15621-15625, 1991.

Wallace, C.J.A. and Clark-Lewis, I. Using solid phase peptide synthesis for the incorporation of non-coded amino acids into semisynthetic protein analogues. In: Proceedings of the European Peptide Symposium, eds. Giralt, E. and Andreau, D., Escom, Leiden, The Netherlands, pp 229-231, 1991.

Walz, A., Meloni, F., Clark-Lewis, I., von Tscharner, V. and Baggiolini, M. (Ca2+) changes and respiratory burst in human neutrophils and monocytes by NAP-1/interleukin-8, NAP-2 and gro/MGSA, J. Leukoc. Biol. 50: 239-286, 1991.

Welham, M.J. and Schrader, J.W. Modulation of c-kit mRNA and protein by hemopoietic growth factors. Mol. Cell. Biol. 11: 2901-2904 (1991).

Wettenhall, R.E.H., Aebersold, R., Hood, L.E. Solid-phase sequencing of 32p labelled phosphopeptides. Methods Enzymol., Vol 201 186-199, 1991.

Yeung, D.E., Brown, G.W., Tam, P., Russnak, R.H., Wilson, G., Clark-Lewis, I. and Astell, C.R. Monoclonal antibodies to the major non-structural nuclear protein of minute virus of mice. Virology 181: 35-45, 1991.

Books and Book Chapters

Schrader, J.W. Interleukin-3: Structure and Function in Health and Disease, In: The Cytokine Handbook, ed. Thomson, A.W., Academic Press London, pp 103-118, 1991.

Schrader, J.W., Clark-Lewis, I., Leslie, K.B. and Ziltener, H.J. Interleukin-3. In: Human Cytokines: Handbook for Basic and Clinical Research, eds. Aggarwal, B.B. and Gutterman, J.V., Blackwell Scientif. Publicat. Ltd., Cambridge, MA, pp 96-110, 1991.

Schrader, J.W., Reinish, C.A., Moyer, C. Vascular smooth muscle cells: Cytokine production and implications for the pathogenesis of vasculitis and atheroma. In: Cytokine Interactions and Their Control, eds. Baxter, A. and Ross, R., John Wiley & Sons, Chichester, England, pp 140-143, 1991.