The Biomedical Research Centre

Journal Articles

Agrez, M.V., Meldrum, C.J., Sim, A.T., Aebersold, R., Clark, I.M., Cawston, T.E., and Burns, G. A fibroblast elongation factor purified from colon carcinoma cells shares sequence identity with TIMP-1. Biochem. Biophys. Res. Commun., 206:590-600 (1995).

Amankwa, L.N., Harder, K.W., Jirik, F., and Aebersold, R. High-sensitivity determination of tyrosine-phosphorylated peptides by on-line enzyme reactor and electrospray ionization mass spectrometry. Protein Science, 4:113-125 (1995).

Blair, E.D., Roberts, C.M. and Clark-Lewis, I. A simple and rapid TAR-dependent in vitro transcription assay using T cell nuclear extracts and synthetic tat1-86 protein, J. Biomed. Sci., 2:136-145 (1995).

Carlow, A.C., Marth, J.M., Clark-Lewis, I. and Teh, H.S. Isolation of a gene encoding a developmentally regulated T cell specific protein with a GTP binding motif, J. Immunol., 154:1724-1734 (1995).

Clark-Lewis, I., Kim, K.-S., Rajarathnam, K., Gong, J.-H., Dewald, B., Baggiolini, M. and Sykes, B.D. Structure-activity relationships of chemokines, J. Leuk. Biol., 57:703-711 (1995).

Dechert, U., Affolter, M., Harder, K.W., Matthews, T., Owen, P., Clark-Lewis, I., Thomas, M.L., Aebersold, R. and Jirik, F. Comparison of the specificity of bacterially expressed cytoplasmic protein-tyrosine phosphatases SHP and SH-PTP2 towards synthetic phosphopeptide substrates, Eur. J. Biochem., 231:673-681 (1995).

Dutz, J., Ong, C.J., Marth, J.D., and Teh, H.-S. Distinct differentiative stages of CD4+CD8+ thymocyte development defined by the lack of coreceptor binding in positive selection. J. Immunol., 154:2588-2599
(1995).

Gong, J.-H. and Clark-Lewis, I. Antagonists of monocyte chemoattractant protein-1 identified by modification of functionally critical NH2-terminal residues, J. Exp. Med., 181:631-640 (1995).

Gong, J.-H., and Clark-Lewis, I. Antagonists of monocyte chemoattractant
protein-1 identified by modification of functionally critical NH2-terminal
residues. J. Exp. Med., 181:631-640 (1995).

Isakov, N., Wange, R.L., Burgess, W.H., Watts, J.D., Aebersold, R., and Samelson, L.E. ZAP-70 binding specificity to T cell receptor tyrosine-based activation motifs: the tandem SH2 domains of ZAP-70 bind distinct TAMs with varying affinity. J. Exp. Med., 181:375-380 (1995).

Mire-Sluis, A.R., Das, R.G., Thorpe, R., and Participants of the Collaborative Study. The international standard for granulocyte colony stimulating factor (G-CSF). Evaluation in an international collaborative study. J. Immunol. Methods, 179:117-126 (1995).

Mire-Sluis, A.R., Das, R.G., Thorpe, R., and Participants of the Collaborative Study. The international standard for granulocyte- acrophage colony stimulating factor (GM-CSF). Evaluation in an international collaborative study. J. Immunol. Methods, 179:127-135 (1995).

Ng, D., Harder, K.W., Clark-Lewis, I., Jirik, F. and Johnson, P. Non radioactive method to measure protein tyrosine phosphatase activity isolated directly from cells, J. Immunol. Meth., 179:177-185 (1995).

Ng, D., Harder, K.W., Clark-Lewis, I., Jirik, F., and Johnson, P. Non-radioactive method to measure tyrosine phosphatase activity isolated directly from cells. J. Immunol. Meth., 179:177-185 (1995).

Pelech, S.L. Commentary - Degenerative and protective signaling mechanisms in the neurofibrillary pathology of Alzheimer's disease. Neurobiol. Aging, 16:458 (1995).

Pelech, S.L. Networking with proline-directed protein kinases implicated in tau phosphorylation. Neurobiol. Aging, 16:247-261 (1995).

Rajarathnam, K., Clark-Lewis, I. and Sykes, B.D. 1H NMR solution structure of an active monomeric IL-8 , Biochemistry, 34:12983-12990 (1995).

Wange, R.L., Isakov, N., Burke, T.R. Jr., Otaka, A., Roller, P.P., Watts, J.D., Aebersold, R., and Samelson, L.E. F2(Pmp)2-TAM zeta 3, a novel competitive inhibitor of the binding of ZAP-70 to the T cell antigen receptor, blocks early T cell signaling. J. Biol. Chem., 270:944-948(1995).

Weber, M., Uguccioni, M., Ochensberger, B., Baggiolini, M., Clark-Lewis, I. and Dahinden, C.A. Monocyte chemotactic protein MCP-2 activates human basophil and eosinophil leukocytes similar to MCP-3, J. Immunol., 154:4166-4172 (1995).

Welham, M.J., Learmonth, L., Bone, H., and Schrader, J.W. IL-13 signal transduction in lymphohemopoietic cells: Similarities and differences in signal transduction with IL-4 and insulin, J. Biol. Chem., 270:12286-12296 (1995).