The Biomedical Research Centre

Journal Articles

Arenzana-Seisdedos, F., Amara, A., Thomas, D., Virelizier, J.L., Baleux, F., Clark-Lewis, I., Legler, D.F., Moser, B. and Baggiolini, M. b-chemokine MDC and HIV infection. Science, 281:487a (1998).

Crump, M.P., Rajarathnam, K., Kim, K.-S., Clark-Lewis, I. and Sykes, B.D. Solution structure of eotaxin, a chemokine that selectively recruits eosinophils in allergic inflammation. J. Biol. Chem., 273:22471-22479 (1998).

Ferro, V., Weiler, L., Withers, S.G. and Ziltener, H.J. N-Glycosyl Phosphonaminates: Potential Transition State Analogue Inhibitors of Glycopeptidases. Canadian J. of Chem., 76: 313-318 (1998).

Fellinger, W., Barran, P., Merkens, H., Corbel, S.Y. and Ziltener, H.J. In vivo overexpression of core 2 N-acetyl-glucosaminyltransferase prevents repopulation of the bone marrow with colony forming cells but fails to affect normal T cell development. J. Cell. Physiol., 176: 350-358 (1998).

Foltz, I.N., Gerl, R.E., Wieler, J.S., Luckach, M., Salmon, R.A. and Schrader, J.W. Human mitogen-activated protein kinase kinase 7 (MKK7) is a highly conserved c-Jun N terminal kinase/stress-activated protein kinase (JNK/SAPK) kinase activated by environmental stresses and physiological stimuli. J. Biol. Chem., 273(15):9344-9351 (1998).

Geras-Raaka, E., Varma, A., Clark-Lewis, I. and Gershengorn, M.C. Human IP10 inhibits constitutive signaling if Kaposi's sarcoma associated Hepes virus G protein coupled receptor. J. Exp. Med., 188:405-408 (1998).

Geras-Raaka, E., Varma, A., Clark-Lewis, I. and Gershengorn, M.C. Kaposi's sarcoma-associated herpesvirus (KSHV) chemokine vMIP-II and human SDF-1 alpha inhibit signaling by KSHV G protein-coupled receptor. Biochem. Biophys. Res. Commun., 253(3):725-727 (1998).

Gershengorn, M.C, Geras-Raaka, G., Varma, A. and Clark-Lewis, I. Chemokines activate Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor in mammalian cells in culture. J. Clin. Invest., 102:1469-1472 (1998).

Hadida, F., Vieillard, V., Autranm, B., Clark-Lewis, I., Baggiolini, M. and Debre, P. HIV-specific T cell cytoxicity mediated by RANTES vis the chemokine receptor CCR3. J. Exp. Med., 188:609-614 (1998).

Legler, D.F., Loetscher, M., Stuber-Roos, R., Clark-Lewis, I., Baggiolini, M. and Moser, B.M. BCA-1, a human CXC chemokine expressed in lymphoid tissues, selectively attracts B lymphocytes via BLR1/CXCR5 J. Exp. Med., 187: 655-660 (1998).

Loetscher, P., Gong, J.-H., Dewald, B., Baggiolini, M. and Clark-Lewis, I. N-terminal peptides of SDF-1 with CXCR4 agonist and antagonist properties. J. Biol. Chem., 273:22279-22283 (1998).

McLean, G.R., Williams, M.J., Woodhouse, C.S. and Ziltener, H.Z. Transcobalamin II and in vitroProliferation of Leukemic Cells. Leukemia and Lymphoma, 30:101-109 (1998).

Piali, L., Weber, C., La Rosa, G., Mackay, C.R., Springer, T.A., Clark-Lewis, I. and Moser, B. The chemokine receptor CXCR3 mediates rapid and shear resistant adhesion induction by the chemokines IP10 and Mig. Eur. J. Immunol., 28:961-972 (1998).

Tessier, P.A., Naccache, P.H., Diener, K.R., Gladue, R.P., Neote, K.S., Clark-Lewis, I. and McColl, S.R. Induction of acute inflammation in vivo by staphylococcal superantigens. II. Critical role for chemokines, ICAM-1, and TNF-alpha. J. Immunol., 161:1204-1211(1998).

Willimann, K., Legler, D.F., Loetscher, M., Roos, R.S., Delgado, M.B., Clark-Lewis, I., Baggiolini, M. and Moser, B. The chemokine SLC is expressed in T cell areas of lymph nodes and mucosal lymphoid tissues and attracts activated T cells via CCR7. Eur. J. Immunol., 28:2025-2034 (1998).

Wolf, M., Belen-Delgado, M., Jones, S., Dewald, B., Clark-Lewis, I. and Baggiolini, M. Granulocyte chemotactic protein 2 (GCP-2) acts via both IL-8 receptors CXCR1 and CXCR2. Eur. J. Immunol, 28: 164-170 (1998).

Books and Book Chapters

Clark-Lewis, I., Anderson, J., Owen, P.L., Vo, L. and Gong, J.-H. Structure activity relationships of growth factors and chemokines. In: Growth factors and receptors: a practical approach, eds. McKay, I.A. and Brown, K.D., Oxford University Press, pp. 109-124 (1998).

Clark-Lewis, I. Chemokine synthesis. In: Methods in Molecular Biology, (1998).

Schrader, J.W. Interleukin-3 In: The Cytokine Handbook, 3rd Edition (ed. Thompson, A.), Academic Press Ltd., London, pp. 105-132 (1998).