The Biomedical Research Centre

Journal Articles

Baird, J.W., Nibbs, R.J.B., Komi-Koma, M., Connolly, J.A., Ottersbach, K., Clark-Lewis, I., Liew, F.Y. and Graham, G.J. ESkine, a novel b-chemokine is differentially spliced to produce secretable and nuclear targeted isoforms. J. Biol. Chem., 274:33496-33503 (1999).

Carlow, D.A., Ardman, B. and Ziltener, H.J. A novel CD8 T cell restricted CD45RB epitope shared by CD43 is differentially affected by glycosylation. J. Immunol., 163:1441-1448 (1999).

Cashman, J.D., Clark-Lewis, I., Eaves, A.C., and Eaves, C.J. Differentiation stage-specific regulation of primitive human hematopoietic progenitor cycling by exogenous and endogenous inhibitors in an in vivomodel. Blood, 94:3722-3729 (1999).

Charlton, L.A., Sayed, M., Clark-Lewis. I., Aebersold, R. and Pelech, S.L. "Characterization of an activiated ribosomal S6 kinase variant from maturing sea star oocytes: association with phosphatase 2A and substrate specificity", J. Cell. Biochem., 75:310-326 (1999).

Crump, M.P., Spyracopoulos, L., Lavigne, P., Kim, K.-S., Clark-Lewis, I. and Sykes, B.D. Backbone dynamics of human CC chemokine eotaxin supports the scaffold hypothesis of chemokine structure and function. Protein Sci., 8:2041-2054 (1999).

Ehrhardt, G.R.A, Leslie, K.B., Lee, F., Wieler, J.S. and Schrader, J.W. M-Ras, a widely expressed 29 kDa homologue of p21 Ras; expression of a constitutively active mutant results in factor-independent growth of an IL-3 dependent cell-line. Blood, 94(7):2433-2444 (1999).

Hadida, F., Vieillard, V., Mollet, L., Clark-Lewis, I., Baggiolini, M. and Debre, P. Cutting edge: RANTES regulates Fas ligand expression and killing by HIV-specific CD8 cytotoxic T cells. J. Immunol., 163:1105-1109 (1999).

Lampisuo, M., Liipo, J., Vainio, O., McNagny, K.M., Kulmara, J., Lassila, O. Characterization of prethymic progenitors within the chicken embryo. Int. Immunol.,11: 63-69 (1999).

Levings, M.K. and Schrader, J.W. IL-4 inhibits the production of TNF-alpha and IL-12 by STAT-6 dependent and independent mechanisms. J. Immunol., 162(9):5224-5229 (1999).

Levings, M.K., Bessette, D.C. and Schrader, J.W. Interleukin-4 Synergizes with Raf-1 to Promote Long-term Proliferation and Activation of c-jun N-terminal kinase. Blood, 93(11):3694-3702 (1999).

McColl, S.R. and Clark-Lewis, I. Inhibition of murine neutrophil recruitment in vivo by CXC chemokine receptor antagonists. J. Immunol., 163:2829-2035 (1999).

Orban, P.C., Levings, M.K. and Schrader, J.W. Heterodimerization of the alpha and beta chains of the IL-3 receptor is necessary and sufficient for IL-3 induced mitogenesis. Blood, 94(5):1-10 (1999).

Orchansky, P.L., Kwan, R., Lee, F. and Schrader, J.W. Characterization of the Cytoplasmic Domain of IL-13 Receptor-alpha J. Biol. Chem., 274(30):20818-20825 (1999).

Rajarathnam, K., Crump, M.P., Clark-Lewis, I., Sykes, B.D. Spectroscopic characterization of chemokines: relevance for quality control and standardization. Developments in Biological Standardization, 97: 49-57 (1999).

Rajarathnam, K., Sykes, B.D., Dewald, B., Baggiolini, M. and Clark-Lewis, I. Disulfide bridges in interleukin-8 probed using non-natural disulfide analogs: dissociation of roles in structure from function. Biochemistry, 38:7653-7658 (1999).

Scheid, M., Foltz, I.N., Young, P.R., Schrader, J.W. and Duronio, V. Ceramide and Cyclic Adenosine Monophosphate (cAMP) Induce cAMP Response Element Binding Protein Phosphorylation via Distinct Signaling Pathways While Having Opposite Effects on Myeloid Cell Survival. Blood, 93:217-225 (1999).

Weber, K.S., von Hundelshausen, P., Clark-Lewis, I., Weber, P.C. and Weber, C. Differential immobilization and hierarchical involvement of chemokines in monocyte arrest and transmigration on inflamed endothelium in shear flow [In Process Citation]. Eur. J. Immunol., 29(2): 700-712 (1999).