The Biomedical Research Centre

Journal Articles

Auersperg, N. and Ziltener, H. Reproductive hormone-induced, STAT3-mediated interleukin 6 action in normal and malignant human ovarian surface epithelial cells. J. Natl. Cancer Inst. 94(16): 1255-6, 2002.

Blau, H., Brazelton, T., Keshet, G., and Rossi, F.M.V. Something in the eye of the beholder. Science, 298:361, 2002.

Booth, V., Keizer, D.W., Kamphuis, M.B., Clark-Lewis, I., Sykes, B.D. The CXCR3 binding chemokine IP-10/CXCL10: structure and receptor interactions. Biochemistry, 41(33): 10418-25, 2002.

Cashman, J., Clark-Lewis, I., Eaves, A., and Eaves, C. Stromal-derived factor 1 inhibits the cycling of very primitive human hematopoietic cells in vitro and in NOD/SCID mice. Blood, 99(3): 792-9, 2002.

Cashman, J., Dykstra, B., Clark-Lewis, I., Eaves, A., Eaves, C. Changes in the proliferative activity of human hematopoietic stem cells in NOD/SCID mice and enhancement of their transplantability after in vivo treatment with cell cycle inhibitors. J. Exp. Med., 196(9): 1141-1150, 2002.

Clark-Lewis, I., Mattioli, I., Gong, J.H. Loetscher, P. Structure-function relationship between the human chemokine receptor CXCR3 and its ligands. J. Biol. Chem., 278: 289-95, 2002.

Corbel, Y.S. and Rossi, F.M.V. Latest developments and in vivo use of the Tet system: ex vivo and in vivo delivery of tetracycline-regulated genes. Curr. Opin. biotechnol., 13: 448, 2002.

Demeule, M., Poirier, J., Jodoin, J., Bertrand, Y., Desrosiers, R.R., Dagenais, C., Nguyn, T., Gabathuler, R., Kennard, M., Jefferies, W.A., Karkan, D., Tsai, S., Fenart, L., Cecchelli, R., Beliveau, R. High transcytosis of melanotransferrin (P97) across the blood-brain barrier. J. Neurochem., 83(4): 924-922, 2002.

Drew, E., Merkens, H., Chelliah, S., Doyonnas, R., and McNagny, K. CD34 is a specific marker of mature murine mast cells. Exp. Hematol., 10:1211, 2002.

Frevert, C.W., Goodman, R.B., Kinsella, M.G., Kajikawa, O., Ballman, K., Clark-Lewis, I., Proudfoot, A.E., Wells, T.N. and Martin, T.R. Tissue-specific mechanisms control the retention of IL-8 in lungs and skin. J. Immunol., 168(7): 3550-6, 2002.

Glimm, H., Tang, P., Clark-Lewis, I., von Kalle, C. and Eaves, C. Ex vivo treatment of proliferating human cord blood stem cells with stroma-derived factor-1 enhances their ability to engraft NOD/SCID mice. Blood, 99(9): 3454-7, 2002.

Grill, B. and Schrader, J.W. Activation of Rac-1, Rac-2 and Cdc42 by hemopoietic growth factors or cross-linking of the B lymphocyte for antigen. Blood, 100(9): 3183-92, 2002.

Kast, J. and Wilm, M. Sequencing of Neuropeptides by Nanoelectrospray Mass Spectrometry in: J. Silberring and R. Ekman (eds) Mass Spectrometry and Hyphenated Techniques in Neuropeptide Research, John Wiley & Sons, NY, (in press), 2002.

McNagny, K. and Graf, T. Making eosinophils through subtle shifts in transcription factor expression. J. Exp. Med., 195(11): F43-7, 2002.

McQuibban, G.A., Gong, J.H., Wong, J.P., Wallace, J.L., Clark-Lewis, I., Overall, C.M. Matrix metalloproteinase processing of monocyte chemoattractant proteins generates CC chemokine receptor antagonists with anti-inflammatory properties in vivo. Blood, 100(4): 1160-7, 2002.

Mey A., Gandrillon O., McNagny K.M., Clegg D.O., Samarut J. The v-erbA oncogene blocks expression of alpha2/beta1 integrin a normal inhibitor of erythroid progenitor proliferation.Oncogene. Apr. 25:21
(18):2864-72, 2002.

Moise A.R., Grant J.R., Vitalis T. Z. and Jefferies,W.A. Adenovirus E3-6.7K Maintains Calcium Homeostasis and Prevents Apoptosis and Arachidonic Acid Release. Journal of Virology. 76(4):1578-1587, 2002.

Nielsen, J.S., Doyonnas, R. and McNagny, K.M. Avian models to study the transcriptional control of hematopoietic lineage commitment and to identify lineage-specific genes. Cells Tissues Organs 171(1): 44-63, 2002.

Overall, C.M., McQuibban, G.A., Clark-Lewis, I. Discovery of chemokine substrates for matrix metalloproteinases by exosite scanning: a new tool for degradomics. Biol. Chem., 383(7-8): 1059-66, 2002.

Pungente, MD, Weiler, L and Ziltener, HJ. Antibody-Catalyzed Formation of a 14-membered Ring Lactone. Canadian J. of Chemistry 80:1643-1645 2002.

Ujiie, M., Dickstein, D.L. and Jefferies, W.A. p97 as a biomarker for Alzheimer disease. Front Biosci. 7: 342-7 Review, 2002.

Valdez, Y., Mah, W., Winslow, M.M., Xu, L., Ling, P. and Townsend, S.E. Major histocompatibility complex class II presentation of cell-associated antigen is mediated by CD8alpha+ dendritic cells in vivo. J. Exp. Med., 195(6): 683-94, 2002.

Westermarck, J., Weiss, C., Saffrich, R., Kast, J., Musti, A., Wessely, M., Ansorge, W., Seraphin, B., Wilm, M., Valdez, B. and Bohmann, D. The DexH/D-box RNA helicase RHII/Gu is a co-factor for c-Jun-mediated transcription activation. EMBO J., 21, 451-460, 2002.

Books and Book Chapters

Rossi, F.M.V. and Blau, H.M. Regulatable vectors. Entry for the Encyclopedia of Molecular Medicine (in press), 2002.

Schrader, J.W., Schallhorn, A., Grill, B., and Guo, Xuecui. Activation of small GTPases and Rho family by growth factors active on mast cells. Mol. Immunology. Vol 38/16-18: 1181-1186, 2002.

Ehrhardt, A., Ehrhardt, G., Guo, X. and Schrader, J.W. Ras and relatives: job sharing and networking keep an old family together. Exp. Hematol., (10): 1989, 2002.