The Biomedical Research Centre

Journal Articles

Booth, V, Slupsky, CM, Clark-Lewis, I, Sykes, BD. Unmasking ligand binding motifs: identification of a chemokine receptor motif by NMR studies of antagonist peptides. J. Mol. Biol., 327: 329-34, 2003.

Carlow, D.A., Williams, M.J., Ziltener, H.J. Modulation of o-glycans and N-glycans on murine CD8 T cells fails to alter annexin v ligand induction by galectin 1. J. Immunol., 171: 5100-6, 2003.

Cashman, J., Dykstra, B., Clark-Lewis, I., Eaves, A., Eaves, C. Changes in the proliferative activity of human hematopoietic stem cells in NOD/SCID mice and enhancement of their transplantability after in vivo treatment with cell cycle inhibitors. J. Exp. Med., 196: 1141-9, 2003.

Clark-Lewis, I., Mattioli, I., Gong, J.H. Loetscher, P. Structure-function relationship between the human chemokine receptor CXCR3 and its ligands. J. Biol. Chem., 278:289-95, 2003.

Corbel, S.Y., Lee, A., Yi, L., Duenas, J., Brazelton, T.R., Blau, H.M., Fossi, F.M. Contribution of hematopoietic stem cells to skeletal muscle. Nat. Med. 9: 1528-32, 2003.

Guo, X, Gerl, RE and Schrader, JW. Defining the involvement of p38a MAP kinase in the production of anti- and pro-inflammatory cytokines using an SB 203580-resistant form of the kinase. J. Biol. Chem. 278:22237-42, 2003.

Kohler, RE, Caon, AC, Willenborg, DO, Clark-Lewis, I, McColl, SR. A role for macrophage inflammatory protein-3alpha/CC chemokine ligand 20 in immune priming during T cell-mediated inflammation of the central nervous system. J. Immunol., 170: 6298--6306, 2003.

Kotturi, M.F., Carlow, D.A., Lee, J.C., Ziltener, H.J., Jefferies, W.A. Identification and functional characterization of voltage-dependent calcium channels in T lymphocytes. J. Biol. Chem., 278: 46949-60, 2003.

Lizee, G., Basha, G., Tiong, J., Julien, J.P., Tian, M., Biron, K.E., Jefferies, W.A. Control of dendritic cell cross-presentation by the major histocompatibility complex class I cytoplasmic domain. Nat. Immunol. 4: 1065-73, 2003.

Luttichau, HR, Clark-Lewis, I, Jensen, PO, Moser, C, Gerstoft, J, Schwartz, TW. A highly selective CCR2 chemokine agonist encoded by human herpesvirus 6. J. Biol. Chem., 278: 10928-33, 2003.

McNagny, K. and Graf, T. E26 leukemia virus converts primitive erythroid cells into cycling multilineage progenitors. Blood, 101: 1103-10, 2003.

Moroo, I., Ujiie, M., Walker, B.L., Tiong, J.W., Vitalis, T.Z., Karkan, D., Gabathuler, R., Moise, A.R., Jefferies, W.A. Identification of a Novel Route of Iron Transcytosis across the Mammalian Blood-Brain Barrier. Microcirculation. 10: 457-462, 2003.

Ogilvie, P, Paoletti, S, Clark-Lewis, I, Uguccioni, M. Eotaxin-3 is a natural antagonist for CCR2 and exerts a repulsive effect on human monocytes. Blood, 102: 789-94, 2003.

Proudfoot, AE, Handel, TM, Johnson, Z, Lau, EK, LiWang, P, Clark-Lewis, I, Borlat, F, Wells, TN, Kosco-Vilbois, MH. Glyosaminoglycan binding and oligomerization are essential for the in vivo activity of certain chemokines. Proc. Natl. Acad. Sci. USA, 100: 19885-90, 2003.

Schrader, JW. Interleukin is as interleukin does. J. Immunol. Methods, 276:1-3, 2003.

Ujiie, M., Dickstein, D.L., Carlow, D.A., Jefferies, W.A. Blood-brain barrier permeability precedes senile plaque formation in an Alzheimer disease model. Microcirculation. 10: 463-70, 2003.

Webb, L.M., Clark-Lewis, L., Alcami, A. The gammaherpesvirus chemokine binding protein binds to the N terminus of CXCL8. J. Virol., 77: 8588-92, 2003.

Wolf, M, Clark-Lewis, I, Buri, C, Langen, H, Lis, M, Mazzucchelli, L. Cathepsin D specifically cleaves the chemokines macrophage inflammatory protein-1 alpha, macrophage inflammatory protein-1 beta, and SLC that are expressed in human breast cancer. Am. J. Pathol., 162: 1183-90, 2003.

Zhang, K., McQuibban, G.A., Silva, D., Butler, G.S., Johnston, J.B., Holden, J., Clark-Lewis, I., Overall, C.M., Power, C. HIV-induced metalloproteinase processing of the chemokine stromal cell derived factor-1 causes neurodegeneration. Nat. Neurosci., 6: 1064-71, 2003.